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Here, we describe the type of research we are interested in. If you are motivated and hard-working and you want to contribute to our research, please contact us!


You can also visit my profile on Research Gate here.

Publications


Pascal Bernard and Vincent Vanoosthuyse*. Does transcription play a role in creating a condensin binding site? Transcription. (pdf).
* corresponding author

Pénélope Legros, Amélie Malapert, Sho Niinuma, Pascal Bernard and Vincent Vanoosthuyse*. RNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genes. PLoS Genet. 2014 Nov 13;10(11):e1004794. doi: 10.1371/journal.pgen.1004794.
* corresponding author 

Vincent Vanoosthuyse*, Pénélope Legros, Sjaak J.A. van der Sar, Gaël Yvert, Kenji Toda, Thierry Le Bihan, Yoshinori Watanabe, Kevin Hardwick and Pascal Bernard. CPF-associated phosphatase activity opposes Condensin-mediated chromosome condensation. PLoS Genet 10(6): e1004415. doi:10.1371/journal.pgen.1004415 
* corresponding author

Hyun-Soo Kim, Rituparna Mukhopadhyay, Scott B. Rothbart, Andrea C. Silva, Vincent Vanoosthuyse, Ernest Radovani, Thomas Kislinger, Assen Roguev, Colm J. Ryan, Jiewei Xu et al : Identification of a novel Bromodomain / Casein Kinase II / TAF-containing complex as a regulator of mitotic condensin function. Cell reports 2014; (13;6(5):892-905).
 
John C Meadows, Lindsey A Shepperd, Vincent Vanoosthuyse, Theresa C Lancaster, Alicja M Sochaj, Graham J Buttrick, Kevin G Hardwick, Jonathan B A Millar: Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors. Developmental cell 2011; 20(6):739-50.

Buttrick GJ, Meadows JC, Lancaster TC, Vanoosthuyse V, Shepperd LA, Hoe KL, Kim DU, Park HO, Hardwick KG, Millar JB. Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B. Mol Biol Cell. 2011 Dec;22(23):4486-502

Vincent Vanoosthuyse*, Kevin G Hardwick: Overcoming inhibition in the spindle checkpoint. Genes & development 2009; 23(24):2799-805.
* joint corresponding author

Hyun-Soo Kim, Vincent Vanoosthuyse*, Jeffrey Fillingham, Assen Roguev, Stephen Watt, Thomas Kislinger, Alex Treyer, Laura Rocco Carpenter, Christopher S Bennett, Andrew Emili, Jack F Greenblatt, Kevin G Hardwick, Nevan J Krogan, Jürg Bähler, Michael-Christopher Keogh: An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe. Nature Structural & Molecular Biology 2009; 16(12):1286-93.
* joint first and corresponding author

Vincent Vanoosthuyse*, John C Meadows, Sjaak J A van der Sar, Jonathan B A Millar, Kevin G Hardwick: Bub3p facilitates spindle checkpoint silencing in fission yeast. Molecular biology of the cell 2009; 20(24):5096-105.
* joint corresponding author

Vincent Vanoosthuyse*, Kevin G Hardwick: A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism. Current biology 2009; 19(14):1176-81.
* joint corresponding author

Vincent Vanoosthuyse, Sergey Prykhozhij, Kevin G Hardwick: Shugoshin 2 regulates localization of the chromosomal passenger proteins in fission yeast mitosis. Molecular Biology of the Cell 2007; 18(5):1657-69.

Vaur S, Cubizolles F, Plane G, Genier S, Rabitsch PK, Gregan J, Nasmyth K, Vanoosthuyse V, Hardwick KG, Javerzat JP: Control of Shugoshin function during fission-yeast meiosis. Curr Biol. 2005 Dec 20;15(24):2263-70.

Kadura S, He X, Vanoosthuyse V, Hardwick KG, Sazer S. The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint function. Mol Biol Cell. 2005 Jan;16(1):385-95.

Vincent Vanoosthuyse, Kevin G Hardwick: Bub1 and the multilayered inhibition of Cdc20-APC/C in mitosis.Trends in Cell Biology 2005; 15(5):231-3.

Vincent Vanoosthuyse, Rebekka Valsdottir, Jean-Paul Javerzat, Kevin G Hardwick: Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p. Molecular and Cellular Biology 2004; 24(22):9786-801.

Gabrielle Tichtinsky, Vincent Vanoosthuyse , J Mark Cock, Thierry Gaude: Making inroads into plant receptor kinase signalling pathways. Trends Plant Sci. 2003 May;8(5):231-7.
J Mark Cock, Vincent Vanoosthuyse, Thierry Gaude: Receptor kinase signalling in plants and animals: distinct molecular systems with mechanistic similarities. Curr Opin Cell Biol. 2002 Apr;14(2):230-6.

Vincent Vanoosthuyse, Gabrielle Tichtinsky, Christian Dumas, Thierry Gaude, J Mark Cock: Interaction of calmodulin, a sorting nexin and kinase-associated protein phosphatase with the Brassica oleracea S locus receptor kinase. Plant physiology 2003; 133(2):919-29.

Vincent Vanoosthuyse, Christine Miege, Christian Dumas, J. Mark Cock: Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response. Plant Molecular Biology 2001; 46(1):17-34.



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